')}.amp-carousel-button-prev{background-image:url('data:image/svg+xml;charset=utf-8,Previous ')}.ampstart-dropdown{min-width:200px}.ampstart-dropdown.absolute{z-index:100}.ampstart-dropdown.absolute>section,.ampstart-dropdown.absolute>section>header{height:100%}.ampstart-dropdown>section>header{background-color:#000;border:0;color:#fff}.ampstart-dropdown>section>header:after{display:inline-block;content:"+";padding:0 0 0 1.5rem;color:#003f93}.ampstart-dropdown>[expanded]>header:after{content:"�"}.absolute .ampstart-dropdown-items{z-index:200}.ampstart-dropdown-item{background-color:#000;color:#003f93;opacity:.9}.ampstart-dropdown-item:active,.ampstart-dropdown-item:hover{opacity:1}.ampstart-footer .ampstart-icon{fill:#000}.ampstart-footer .ampstart-social-follow li:last-child{margin-right:0}.ampstart-image-fullpage-hero{color:#fff}.ampstart-fullpage-hero-heading-text,.ampstart-image-fullpage-hero .ampstart-image-credit{-webkit-box-decoration-break:clone;box-decoration-break:clone;background:#000;padding:0 1rem .2rem}.ampstart-image-fullpage-hero>amp-img{max-height:calc(100vh - 3.5rem)}.ampstart-image-fullpage-hero>amp-img img{-o-object-fit:cover;object-fit:cover}.ampstart-fullpage-hero-heading{line-height:3.5rem}.ampstart-fullpage-hero-cta{background:transparent}.ampstart-readmore{background:-webkit-linear-gradient(bottom,rgba(0,0,0,.65),transparent);background:linear-gradient(0deg,rgba(0,0,0,.65),transparent);color:#fff;margin-top:5rem;padding-bottom:3.5rem}.ampstart-readmore:after{display:block;content:"?";font-size:2rem}.ampstart-readmore-text{background:#000}@media (min-width:52.06rem){.ampstart-image-fullpage-hero>amp-img{height:60vh}}.ampstart-image-heading{color:#fff;background:-webkit-linear-gradient(bottom,rgba(0,0,0,.65),transparent);background:linear-gradient(0deg,rgba(0,0,0,.65),transparent)}.ampstart-image-heading>*{margin:0}amp-carousel .ampstart-image-with-heading{margin-bottom:0}.ampstart-image-with-caption figcaption{color:#4f4f4f;line-height:1.125rem}amp-carousel .ampstart-image-with-caption{margin-bottom:0}.ampstart-input{max-width:100%;width:300px;min-width:100px;font-size:1rem;line-height:1.5rem}.ampstart-input [disabled],.ampstart-input [disabled]+label{opacity:.5}.ampstart-input [disabled]:focus{outline:0}.ampstart-input>input,.ampstart-input>select,.ampstart-input>textarea{width:100%;margin-top:1rem;line-height:1.5rem;border:0;border-radius:0;border-bottom:1px solid #4a4a4a;background:none;color:#4a4a4a;outline:0}.ampstart-input>label{color:#003f93;pointer-events:none;text-align:left;font-size:.875rem;line-height:1rem;opacity:0;-webkit-animation:.2s;animation:.2s;-webkit-animation-timing-function:cubic-bezier(.4,0,.2,1);animation-timing-function:cubic-bezier(.4,0,.2,1);-webkit-animation-fill-mode:forwards;animation-fill-mode:forwards}.ampstart-input>input:focus,.ampstart-input>select:focus,.ampstart-input>textarea:focus{outline:0}.ampstart-input>input:focus::-webkit-input-placeholder,.ampstart-input>select:focus::-webkit-input-placeholder,.ampstart-input>textarea:focus::-webkit-input-placeholder{color:transparent}.ampstart-input>input:focus::-moz-placeholder,.ampstart-input>select:focus::-moz-placeholder,.ampstart-input>textarea:focus::-moz-placeholder{color:transparent}.ampstart-input>input:focus:-ms-input-placeholder,.ampstart-input>select:focus:-ms-input-placeholder,.ampstart-input>textarea:focus:-ms-input-placeholder{color:transparent}.ampstart-input>input:focus::placeholder,.ampstart-input>select:focus::placeholder,.ampstart-input>textarea:focus::placeholder{color:transparent}.ampstart-input>input:not(:placeholder-shown):not([disabled])+label,.ampstart-input>select:not(:placeholder-shown):not([disabled])+label,.ampstart-input>textarea:not(:placeholder-shown):not([disabled])+label{opacity:1}.ampstart-input>input:focus+label,.ampstart-input>select:focus+label,.ampstart-input>textarea:focus+label{-webkit-animation-name:a;animation-name:a}@-webkit-keyframes a{to{opacity:1}}.ampstart-input>label:after{content:"";height:2px;position:absolute;bottom:0;left:45%;background:#003f93;-webkit-transition:.2s;transition:.2s;-webkit-transition-timing-function:cubic-bezier(.4,0,.2,1);transition-timing-function:cubic-bezier(.4,0,.2,1);visibility:hidden;width:10px}.ampstart-input>input:focus+label:after,.ampstart-input>select:focus+label:after,.ampstart-input>textarea:focus+label:after{left:0;width:100%;visibility:visible}.ampstart-input>input[type=search]{-webkit-appearance:none;-moz-appearance:none;appearance:none}.ampstart-input>input[type=range]{border-bottom:0}.ampstart-input>input[type=range]+label:after{display:none}.ampstart-input>select{-webkit-appearance:none;-moz-appearance:none;appearance:none}.ampstart-input>select+label:before{content:"?";line-height:1.5rem;position:absolute;right:5px;zoom:2;top:0;bottom:0;color:#003f93}.ampstart-input-chk,.ampstart-input-radio{width:auto;color:#4a4a4a}.ampstart-input input[type=checkbox],.ampstart-input input[type=radio]{margin-top:0;-webkit-appearance:none;-moz-appearance:none;appearance:none;width:20px;height:20px;border:1px solid #003f93;vertical-align:middle;margin-right:.5rem;text-align:center}.ampstart-input input[type=radio]{border-radius:20px}.ampstart-input input[type=checkbox]:not([disabled])+label,.ampstart-input input[type=radio]:not([disabled])+label{pointer-events:auto;-webkit-animation:none;animation:none;vertical-align:middle;opacity:1;cursor:pointer}.ampstart-input input[type=checkbox]+label:after,.ampstart-input input[type=radio]+label:after{display:none}.ampstart-input input[type=checkbox]:after,.ampstart-input input[type=radio]:after{position:absolute;top:0;left:0;bottom:0;right:0;content:" ";line-height:1.4rem;vertical-align:middle;text-align:center;background-color:#fff}.ampstart-input input[type=checkbox]:checked:after{background-color:#003f93;color:#fff;content:"?"}.ampstart-input input[type=radio]:checked{background-color:#fff}.ampstart-input input[type=radio]:after{top:3px;bottom:3px;left:3px;right:3px;border-radius:12px}.ampstart-input input[type=radio]:checked:after{content:"";font-size:3rem;background-color:#003f93}.ampstart-input>label,_:-ms-lang(x){opacity:1}.ampstart-input>input:-ms-input-placeholder,_:-ms-lang(x){color:transparent}.ampstart-input>input::placeholder,_:-ms-lang(x){color:transparent}.ampstart-input>input::-ms-input-placeholder,_:-ms-lang(x){color:transparent}.ampstart-input>select::-ms-expand{display:none}.ampstart-headerbar{background-color:#fff;color:#000;z-index:999;box-shadow:0 0 5px 2px rgba(0,0,0,.1)}.ampstart-headerbar+:not(amp-sidebar),.ampstart-headerbar+amp-sidebar+*{margin-top:3.5rem}.ampstart-headerbar-nav .ampstart-nav-item{padding:0 1rem;background:transparent;opacity:.8}.ampstart-headerbar-nav{line-height:3.5rem}.ampstart-nav-item:active,.ampstart-nav-item:focus,.ampstart-nav-item:hover{opacity:1}.ampstart-navbar-trigger:focus{outline:none}.ampstart-nav a,.ampstart-navbar-trigger,.ampstart-sidebar-faq a{cursor:pointer;text-decoration:none}.ampstart-nav .ampstart-label{color:inherit}.ampstart-navbar-trigger{line-height:3.5rem;font-size:2rem}.ampstart-headerbar-nav{-webkit-box-flex:1;-ms-flex:1;flex:1}.ampstart-nav-search{-webkit-box-flex:0.5;-ms-flex-positive:0.5;flex-grow:0.5}.ampstart-headerbar .ampstart-nav-search:active,.ampstart-headerbar .ampstart-nav-search:focus,.ampstart-headerbar .ampstart-nav-search:hover{box-shadow:none}.ampstart-nav-search>input{border:none;border-radius:3px;line-height:normal}.ampstart-nav-dropdown{min-width:200px}.ampstart-nav-dropdown amp-accordion header{background-color:#fff;border:none}.ampstart-nav-dropdown amp-accordion ul{background-color:#fff}.ampstart-nav-dropdown .ampstart-dropdown-item,.ampstart-nav-dropdown .ampstart-dropdown>section>header{background-color:#fff;color:#000}.ampstart-nav-dropdown .ampstart-dropdown-item{color:#003f93}.ampstart-sidebar{background-color:#fff;color:#000;min-width:300px;width:300px}.ampstart-sidebar .ampstart-icon{fill:#003f93}.ampstart-sidebar-header{line-height:3.5rem;min-height:3.5rem}.ampstart-sidebar .ampstart-dropdown header,.ampstart-sidebar .ampstart-dropdown-item,.ampstart-sidebar .ampstart-faq-item,.ampstart-sidebar .ampstart-nav-item,.ampstart-sidebar .ampstart-social-follow{margin:0 0 1.5rem}.ampstart-sidebar .ampstart-nav-dropdown{margin:0}.ampstart-sidebar .ampstart-navbar-trigger{line-height:inherit}.ampstart-navbar-trigger svg{pointer-events:none}.ampstart-related-article-section{border-color:#4a4a4a}.ampstart-related-article-section .ampstart-heading{color:#4a4a4a;font-weight:400}.ampstart-related-article-readmore{color:#000;letter-spacing:0}.ampstart-related-section-items>li{border-bottom:1px solid #4a4a4a}.ampstart-related-section-items>li:last-child{border:none}.ampstart-related-section-items .ampstart-image-with-caption{display:-webkit-box;display:-ms-flexbox;display:flex;-ms-flex-wrap:wrap;flex-wrap:wrap;-webkit-box-align:center;-ms-flex-align:center;align-items:center;margin-bottom:0}.ampstart-related-section-items .ampstart-image-with-caption>amp-img,.ampstart-related-section-items .ampstart-image-with-caption>figcaption{-webkit-box-flex:1;-ms-flex:1;flex:1}.ampstart-related-section-items .ampstart-image-with-caption>figcaption{padding-left:1rem}@media (min-width:40.06rem){.ampstart-related-section-items>li{border:none}.ampstart-related-section-items .ampstart-image-with-caption>figcaption{padding:1rem 0}.ampstart-related-section-items .ampstart-image-with-caption>amp-img,.ampstart-related-section-items .ampstart-image-with-caption>figcaption{-ms-flex-preferred-size:100%;flex-basis:100%}}.ampstart-social-box{display:-webkit-box;display:-ms-flexbox;display:flex}.ampstart-social-box>amp-social-share{background-color:#000}.ampstart-icon{fill:#003f93}.ampstart-input{width:100%}main .ampstart-social-follow{margin-left:auto;margin-right:auto;width:315px}main .ampstart-social-follow li{-webkit-transform:scale(1.8);transform:scale(1.8)}h1+.ampstart-byline time{font-size:18px;font-weight:400}.ampstart-subtitle{text-transform:uppercase}.content-body iframe{max-width:100%}.margin-top-15{margin-top:15px}.margin-top-10{margin-top:10px}.text-red{color:red}.amp-social-share{font-size:14px;padding:5px;width:32%}amp-social-share{background-size:20px}.amp-social-list{position:absolute;bottom:30px}.followus{margin-top:-10px;font-weight:700}.box-artikel-terkait-images amp-img{width:80px;height:80px}.box-artikel-terkait{border-bottom:1px solid #ccc;padding-bottom:2px;padding-top:10px}.box-artikel-terkait-images{float:left}.box-artikel-terkait-images amp-img img{object-fit:cover}.box-artikel-terkait-description small{font-size:11px}.box-artikel-terkait-description p{font-weight:700;font-size:14px}.box-artikel-terkait a{text-decoration:none}.feature-images amp-img img{object-fit:cover}.ads{width:320px;height:auto;text-align:center;margin:70px auto auto}.ads-300{height:250px}.ads-300,.ads-600{width:300px;text-align:center;margin:10px auto auto}.ads-600{height:600px}footer{background-color:#fff}footer ul{margin:0;padding:0}footer a{color:#fff;font-size:12px;font-weight:400;text-transform:none}footer li{list-style:none}.footer-copyright{color:#fff;font-size:14px;text-align:center;padding:10px;background-color:#1d1d1b}.feature-images-video{background-color:#000;padding:20px 0}.content-body p{margin:10px 0}.align-center-button{display:flex;align-items:center;justify-content:center;flex-direction:row;width:100%}amp-web-push-widget .subscribe{display:flex;flex-direction:row;align-items:center;border-radius:2px;border:1px solid #007ae2;padding:6px 20px;font-size:12px;margin:15px 0 0;background:#0e82e5;color:#fff}amp-web-push-widget .subscribe,amp-web-push-widget .unsubscribe{cursor:pointer;outline:0;font-weight:400;-webkit-tap-highlight-color:transparent}amp-web-push-widget .unsubscribe{border-radius:2px;border:1px solid #b3b3b3;margin:0;padding:8px 15px;font-size:15px;background:#bdbdbd;color:#555}amp-web-push-widget .subscribe .subscribe-icon{margin-right:10px}amp-web-push-widget .subscribe:active{transform:scale(.99)}
Herbal Cina Diklaim Mampu Obati Gangguan Autoimun Uzone.id - Sejak dua ribu tahun lalu, tanaman herbal Cina dari jenishydrangea Shang Shan (tumbuh di Nepal dan Tibet) dipercaya mampu mengobati malaria.
Penelitian dari Harvard School of Dental Medicine menunjukkan bahwahalofuginone (HF), senyawa yang berasal dari ekstrak tumbuhan ini, bisa juga digunakan untuk gangguan autoimun.
Senyawa HF ternyata dapat menghalangi perkembangan sel kekebalan yang berbahaya, yang disebut sel Th17. Sel tersebut banyak ditemukan dalam beberapa gangguan autoimun seseorang.
"HF mencegah respon autoimun berbahaya dan menginspirasi pendekatan terapi baru untuk berbagai gangguan autoimun," kata Professor of Developmental Biology Harvard School of Dental Medicine Malcolm Whitman padaSciencedaily , Senin (8/1/2018).
Penelitian ini melibatkan tim peneliti dari Massachuttes General Hospital dan beberapa tempat lain yang diterbitkan jurnal Nature Chemical Biology beberapa waktu lalu.
Penelitian sebelumnya menemukan bahwa HF dapat mengurangi jaringan parut, scleroderma (pengetatan kulit), multiple sclerosis, pembentukan parut, bahkan mencegah perkembangan sel kanker.
Pada tahun 2009, instruktur laboratorium diDepartemen Biologi Harvard School of Dental Medicine Tracy Keller dan rekan melaporkan bahwa HF mampu melindungi tubuh terhadap mutasi sel Th17 tanpa mempengaruhi sel kekebalan baik di dalam tubuh.
Sejak tahun 2006, sel Th17 adalah penyebab utama penyakit autoimun seperti radang usus, rheumatoid arthritis, multiple sclerosis, dan psoriasis. Tim peneliti menemukan dalam dosis tertentu HF menekan penyakit multiple sclerosis pada tikus.
Dengan demikian, HF menjadi senjata baru yang menghambat patologi autoimun tanpa menekan sistem kekebalan tubuh tubuh secara keseluruhan.